Treating POTS is actually very difficult and can be very discouraging for the patient. Sometimes, with the right fitness plan, medications and self-care techniques, some can go into remission and others can have a significant increase in their quality of life. For others, they have exhausted every resource and none have helped. I believe this goes back to the fact that POTS is different for everyone and so is treatment. Below is a list of treatments used by most doctors who treat POTS. This is not an exhaustive list and if you know of anything I missed, please comment below and I will add it.